The cutoff of the differentially expressed metabolites was based on the following two indicators: the p -value of Students t-test was less than 0.05, and the variable importance in the projection (VIP) of the OPLS-DA model was greater than 1
Garlic oil and Helicobacter pylori infection
Flow cytometric analysis The separated leukocytes were stained with fluorescent-conjugated antibodies purchased from BioLegend, BD Biosciences (Franklin Lakes, NJ, USA), Thermo Fisher Scientific, and Tonbo Biomedicine as follows: anti-CD3, anti-CD4, anti-CD8, anti-CD11b, anti-CD11c, anti-CD45, anti-CD45R(B220), anti-CD95, anti-CD117(c-kit), anti-CXCR5, anti-FcRI, anti-GL-7, anti-IgE, anti-Ly6C, anti-Ly6G, anti-PD-1, and anti-Siglec-F (Supplementary Table 1)
Aberrant oligodendroglial-vascular interactions disrupt the bloodbrain barrier, triggering CNS inflammation
Nutrition and Hydration Collagen synthesis requires adequate protein intake, particularly amino acids like glycine, proline, and hydroxyproline
